Cheapest Acid Reflux & Heartburn Medicines (2026)

Proton pump inhibitors and H2 blockers for reflux are cheap generics. Compare the common options.

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1Famotidine (Pepcid)$15$1$14
2Omeprazole$40$2$38
3Pantoprazole (Protonix)$50$3$47
4Esomeprazole (Nexium)$50$3$47

Estimated prices for comparison. Tap any item for full details and current price links.

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